Anastasia Talks about Healthy Babies


You know, very often I'm asked: 'Can you guarantee that our baby will be 100% healthy?' And I understand that all parents want their babies to be healthy. But the reality is that unfortunately, sometimes life gives us bad surprises and babies are born with some kind of disease (I'm not telling specifically about ART here) - scientists of all countries try hard to invent methods to avoid that, but still such things happen.

How many babies are born sick resulting from regular pregnancy - do their parents love them less?
Or, another example - your baby is born healthy but at the age of 5 he gets into car crash - and than you have to take care about a disabled baby - will you love him less?
How human is to speak about 'good quality' and 'bad quality' babies? When I hear such talks I have a desperate desire to remind that we are not manufacturing your kids, we are the clinic which helps this little miracle to happen.

Comments

  1. "We are not manufacturing your kids, we are the clinic which helps this little miracle to happen" - super great thing to hear! They (noone else) are the God to rule over the process. They (noone) else can guarantee your baby is going to be absolutely healthy. Moreover if once having heard this I'd really doubt the clinic's competence. I'd rather take this sort of 'healthy baby guaranteed' like the way to loom my money. Guys at Biotex are honest with their patients. Besides they provide PGD/PGS option to have the opporunity to decide on healthy blasts only. It's known that PGD, preimplantation genetic diagnosis, involves removing a cell from an IVF embryo to test it for a specific genetic condition (cystic fibrosis, for example) before transferring the embryo to the uterus. PGS, preimplantation genetic screening, is the proper term for testing for overall chromosomal normalcy in embryos. PGS is not looking for a specific disease diagnosis - it is screening the embryo for normal chromosome copy number.
    In general, there are 5 main groups of patients that might utilize PGS or PGD.
    Patients that are having IVF with advanced female age - 38 or older (common).
    Patients of any age with repeated IVF failure - usually defined as 3 or more failed attempts.
    To screen for inherited genetic diseases.
    Patients that are carriers of chromosomal translocations.
    Patients that have had recurrent miscarriages.
    If a couple is concerned over any of these, PGD is the way out to feel better.

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    1. Cannot agree more!! If you're finding infertility treatment tough going, you're not alone. It's normal to find such treatments physically and emotionally draining.
      Thankfully, there are a few techniques to try to offset the side effects of your treatments and help you to cope. Here's the fertility expert's suggestions on the matter. (I've come across once & thought it will be helpful to share)~
      'Taking pills such as cabergoline and metformin alongside meals can help to prevent stomach upsets. It may also help to take pills at the same time every day if you have daily pills, or on the same day each week if you have weekly pills. Unwanted side effects will also often improve as your body adjusts to the medicine.
      When you first start taking dopamine-agonists, such as bromocriptine or cabergoline, they can cause your blood pressure to drop and can make you drowsy. It can be safer to take them at bedtime when you'll be lying down anyway.
      If bromocriptine is making you feel sick, placing the tablets directly in your vagina can sometimes help. Do talk to your doctor about this first, though. Placing your tablets in your vagina allows the drug to get into your bloodstream without having to go through your liver first. Side effects such as nausea and diarrhoea often begin in your liver. Your doctor may also be able to prescribe patches as an alternative form of taking the medication.
      If you're having injections, hold an ice-bag next to your skin first, and then warm the injected area afterwards. This can help to prevent pain and bruising. You could also ask your doctor to rotate the site of injections, to help reduce bruising.
      Even milder medications, such as clomifene, can cause breast tenderness, insomnia, irritability or mood swings. Any of these can be hard to live with, or make you hard to live with! But it may be reassuring to know that they're completely normal and don't last beyond the treatment.
      Ovarian swelling is a common side effect of the drugs used for ovulation stimulation during in-vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI). You can look after yourself at home as long as the symptoms are mild. Symptoms may include bloating and discomfort in your belly and nausea. Painkillers prescribed by your doctor, such as paracetamol or codeine, are safe to take and should help to relieve pain. But avoid taking anti-inflammatories, such as ibuprofen or aspirin, as they can affect your kidneys.
      You should also drink water to keep your fluid levels up. Just drink enough so that you don't feel thirsty. Although you may think more fluid is the last thing you need when you're bloated, it will help the rest of your body to keep hydrated.
      Whatever your symptoms, you don't have to suffer in silence. If you're feeling overwhelmed, anxious or depressed, seek out some support. It may help to talk though your worries with a friend or someone in your family.
      Talk to your doctor, too. She may be able to adjust your dosage or switch you to another drug. She may also refer you to a fertility counsellor or support group. You can discuss the difficulty you’re having with fertility drugs in our community.
      Occasionally, the side effects of fertility drugs can be serious. Your doctor will give you information about the warning signs to look out for. You should also be given an emergency number. Call for help at once if you notice:
      Vision problems, including blurred eyesight, or seeing spots, while taking clomifene citrate.
      Allergic reactions to your drugs such as difficulty breathing, tightness in your chest, or swelling of your lips, mouth or tongue.
      The symptoms of severe ovarian hyperstimulation syndrome (OHSS)'.
      Hope this helps.

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  2. We did use PGD at BioTexCom to know our embryos are going to be healthy. I know the process involves either removing a single cell on day 3 cleavage-stage embryos or performing a biopsy on day 5 blastocysts. It has a range of proven medical benefits for both mother and child. I read somwhere, PGD is used to test for more than a hundred specific genetic conditions! Though the testing does not necessarily increase pregnancy rates, it does reduce miscarriages and the incidence of trisomic pregnancies. Since the procedure is performed before implantation, we might feel more comfortable about the future pregnancy. Sadly enough, currently, more than half of couples, with two or more normal embryos and maternal age under 41, will take home a baby on a first IVF-PGD. But anyway this is a great chance of keeping things under control. Of course nobody can guarantee you a healthy baby, surely. But some procedures can be done to avoid complications. Here one should listen to his doctor and follow his advices.

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    1. Thank you for sharing your story. We tried IUI, ICSI and IVF cycles. All the options are great unless you're diagnosed properly for them. My dh had low sperm count and motility so our dr suggested us to try former options. Though he never told my eggs weren't going to work!! Which was very frustrating when we got to know about this issue at biotex which suggested us to look onto egg donation which finally resulted in a healthy baby boy. I believe the most important thing is to choose a good expert/clinic to be with.

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    2. Would love to have shared the tips earlier. I have found them on boards. They were really helpful for me during my tww. 
      Have support either from your partner, relatives, friends.
      Make sure you rest. You do not have to stay in bed but try to relax, watch movies, listen to music, curl up on the sofa and read a book, enjoy a lovely meal. It may be helpful to take some time off work. 
      Keep yourself busy. Distraction is very important during this period of time. 
      Talk to your partner about your feelings. Support for one another is extremely important in making sure that you are mentally and emotionally in the right space. 
      Be aware of the internet. Be careful not to spend the whole two weeks online reading about other women’s experiences and searching for information on signs of positive or negative outcomes of fertility treatments. Too much time online can lead to too much obsessing. 
      Write your thoughts in a journal. You can write your thoughts down throughout the day as they pop up. Or you can do it once a day on regular basis - put all the things that are turning over and over in your mind down on paper and out of your head.
      Use relaxation techniques. Try meditation. Take slow, deep breaths when you are feeling anxious. These techniques can assist you physiologically, as  well as being mentally calming.
      Try to be happy about the present and let the future simply unfold. Be kind to yourself. 

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  3. This opic seems to be very sensitive. Here the first thing I'd say is, if you first look upon ivf process and google its risk and it doesn't take you much time to get such a list:
    Multiple births: IVF increases your risk of multiple births if more than one embryo is implanted in your uterus. If you become pregnant with multiple babies, you may have a higher risk of early labor.
    A premature delivery and a low birth weight.
    Ovarian hyperstimulation syndrome: This occurs when your ovaries become swollen and painful. This syndrome can occur due to the use of injectable fertility drugs. You may experience symptoms like abdominal pain, bloating, nausea, vomiting, and diarrhea. If you become pregnant, you may experience these symptoms for several weeks.
    A miscarriage: Though the rate of miscarriage for women who conceive using IVF is similar to that of women who conceive naturally, the rate can increase as the age of the mother increases. Using frozen embryos during IVF has been known to slightly increase the risk of a miscarriage. [citation needed]
    Complications during the egg-retrieval procedure: The doctor will need to use an aspirating needle to the collect the eggs and this could cause bleeding, infection, or damage to your bowels, bladder, or a blood vessel.
    An ectopic pregnancy: This occurs when the fertilized egg implants outside the uterus, usually in the fallopian tube. About 2 to 5 percent of women who use IVF will have an ectopic pregnancy.
    Birth defects: there is evidence that the rate of birth defects in IVF pregnancies is slightly higher than in spontaneous pregnancies, but the exact mechanism for this is unclear
    .......this list added with every other site....
    So I'm going to ask ''How on Earth one can be sure your baby is absolutely healthy and guarantee this to you??!!'' Preimplantation testings are the option, I fully agree with the posters above..

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    1. There is a lot of information on the subject. They report slightly higher rate of genetic defects in children conceived by ivf. However this results primarily from the fact that infertility as a disease in itself is a risk factor. According to the most recent studies, the risk of genetic disorders is the same in the case of infertile couples which have achieved pregnancy naturally as in the case of patients using ivf. The situation is similar in the case of ICSI, for example. A potentially increased risk results from the cause of the problem and not from the technique itself. Here comes the conclusion. It can’t be stated that ivf as a technique increases the risk of genetic defects.

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    2. I'm through 3 ivf cycles with donor egg. Am on another side of the treatment now but here's a couple of things to share.
      I was told about these side effects after IVF may include:
      Passing a small amount of fluid (may be clear or blood-tinged) after the procedure. Mild cramping. Mild bloating. Constipation. Breast tenderness. I was also told at the clinic to call dr immediately if I happen to experience any of these: Heavy vaginal bleeding. Pelvic pain. Blood in the urine. A fever over 100.5 °F (38 °C).
      Some side effects of fertility medications may include:
      Headaches. Mood swings. Abdominal pain. Hot flashes. Abdominal bloating. Ovarian hyper-stimulation syndrome.
      Hoping for everyone's luck xxx

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  4. PGD is the way out to make sure the embies are great. Though I know the cases (read on different fertility boards) ladies have their A grade, absolutely fine embryos placed back and end up with BFN. Yet others have B grade embryos transferred and get BFP! That's amazing how unpredictable things could be!! And, speaking honestly, every test states 99,9%--yep? This means the med institution always leaves that 1% for any sort of unpredictable nature trick..

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    1. Some literature has reported that PGD can reduce miscarriage rate by 70% and increase the take home baby rate by almost 70%. Although many genetic tests are available, not all are useful or necessary in every individual. Genetic counselors!! help identify which tests, if any, may be most helpful for each particular couple. The goal of genetic counseling is to provide information about the benefits and limitations of those test to help couples make informed decisions. New live being formation is sometimes too fragile..Lots of factors can influence their health and it's important to understand.

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    2. PGD is not 100% accurate. 'cause only several cells are tested. All the rest no. But there IS the possiblity thoe remaining ones may have abnormalties. Besides, the lad performing PGD testing should be a reputable one. in order not to damae embryos whilst testing. This process is not the easiest one.

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  5. We all know that the rate of IVF births has risen dramatically in recent years. 'Cause fertility rates continue to fall worldwide. It's said, events that occur in early development (Including the time between conception and birth) can influence health in later life. Epigenetics plays an important role in this process. Any fertility treatment is often associated with common risk factors, aside from the IVF technology itself. Being older mums or having twins or triplets, which are more likely to be delivered prematurely and have a lower birth weight. Epigenetic differences have been identified in common chronic diseases such as cancer, psychiatric disorders and diabetes. But no such major epigenetic differences in babies conceived by IVF could be found so far. So all those discussions are quite contradicting. But no one/clinic/doc can guarantee you'll have your baby 100% healthy. This is just obvious there are too many reasons which might influence the process. And most of them aren't due to docs or clinics unfortunately.

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  6. The experts argue that extended IVF use increases the risk of harm to both the mother and offspring. Personally I've been through ivf shot resulting in our DD. Then 3 more shots ivf which ended in multiple mcs. Here's the thing to be stressed. Couples should be warned about all potential risks before undergoing IVF. Particularly if they have a reasonable chance of conceiving naturally. Here we should face a choice. But if it goes like the couple CAN NOT concieve without med help, then ivf could be the solution whatever risks it may have.

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  7. We're all lucky nowadays for the possibility of embies screening before transfer. This way the potential of preventing chromosomal and genetic diseases before pregnancy is absolutely possible. The process known as pre-implantation genetic diagnosis has now been available and the technology has progressed rapidly. PGD is used to identify genetic defects in embryos created through in ivf. It can be used to select embryos that have less risk of having a genetic disorders. Increased chances of resulting in a successful pregnancy/ Less cancer predisposition or for sex selection. There are three basic indications for PGD:
    aneuploidy screening;
    translocation analysis;
    single gene disorders.
    In all cases, a woman goes through the whole IVF process (Including ovarian stimulation, egg retrieval, and fertilization.) However, on day three after retrieval, a single cell is removed from the embryo for analysis. If the analysis is good, then the doctor will proceed with an embryo transfer on day five.
    Is this enough for our future kids to be healthy - unfortunately no. But at least those testing done to ensure we're on the right way. (And too low per cent of inaccurate test results).

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  8. My wife and I happened to face a history of multiple miscarriage withing 5 failed ivf rounds. So we began to seek genetic counseling to help find the reason for this continuous outcome. During their genetic counseling session, our health history, family history and previous medical test results were reviewed. We talked about the health of other family members. And their family members’ experiences with pregnancy. The genetic counselor told us about the possibility of a genetic cause for their infertility. We then discussed testing options. Afterall we pursued testing that identifies a genetic change. I think it's called a balanced translocation or sth. The thing we knew it is found in approximately 5 per cent of couples with infertility. We were explained that a balanced translocation is a rearrangement in the chromosomes. And it can cause an increased risk for multiple miscarriages. (Including miscarriages that can occur prior to the woman even realizing she is pregnant!) In addition, there can also be an increased risk to have a baby born with a chromosome abnormality, which can lead to birth defects and developmental delay. The genetic counselor explained all of the risks associated with the balanced translocation as well as our reproductive options, including preimplantation genetic diagnosis. Though it is typically not offered to all couples..All in all, the topic is very sensitive. We all want our kids to be strong and healthy, but there are so many things we cannot keep under the control!

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    1. Surrogacy law is awesome in Ukraine. You're permitted to undergo the process if you and your partner are married. Then a baby is considered to be yours from the moment of conception. The birth certificate is issued with your names. A surro has no right to keep a baby after delivery even if she's changed her mind. This is out of the question in Ukraine. Another thing is that you don't have to struggle in court for this baby to be yours (Like parental order in the UK) or go down the long time process of adopion. How far are you now?

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    2. You'll have to meet one of the requirements then.
      The absence of the uterus;
      Deformation of the cavity or cervix;
      Diseases in which pregnancy and childbirth may endanger a woman’s life;
      At least 3 IVF attempts (this number differs);
      Structural and morphological, or anatomical changes in the endometrium of the uterus;
      Complex somatic diseases.
      Then you should study the surrogacy law within countries on your just perfectly well. Once I was looking for the info on surrogacy in the US and got to know pretty weird things. Waiting time for the first try is about 9 months! American law is very strict. At the same time it's too loyal to the surrogate mothers! For example, surrogate mother during pregnancy has the right to demand anything from the future parents. Often it can grow into blackmail. It doesn’t stop even after the child's birth!! 'cause under American law surrogate mother is allowed to keep in contact with the child!! This is one of common reasons why people don’t choose this country for surrogate program. Plus cost is the highest in the world – around $150k. It's too expensive! All costs have to be paid by parents. Like cesarean section, the cost of treatment rehabilitation, accommodation and food for surrogate mother.
      May I ask are you considering coming to BTC?

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  9. The biggest wish of every parent is to have a healthy baby. Thanks to determining the genetic equipment of embryos problems can be detected in time. Then only healthy embryos that have potential of a successful pregnancy are transferred into the uterus. Genetic abnormalities are a frequent cause of early miscarriages in the first third of the pregnancy. PGD helps to prevent these losses. PGD is suitable if one or both partners have a genetically conditioned disorder in the family.
    PGS is opted by parents who are healthy. They order it preventively. Often these are cases in which previous IVF failed. The analysis reveals most of the problems. Thanks to this analysis you will significantly reduce the risk of a miscarriage or giving birth to a sick child. However not even PGD / PGS are able to detect everything! And the results of the genetic tests are not 100% right. This is for several reasons. Discuss with your dr.

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  10. Here I'd mention preimplantation genetic testing benefits. Embryos are allowed to develop in the incubator until they reach a stage where a small sample can be removed and tested for specific genetic diseases or the correct number of chromosomes. typically after five to six days of development. Embryos that don't contain affected genes or chromosomes can be transferred to your uterus. While preimplantation genetic testing can reduce the likelihood that a parent will pass on a genetic problem, it can't eliminate the risk!! Prenatal testing may still be recommended.

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  11. Needless to say, a gestational carrier runs the risk of a miscarriage like any other pregnancy. If miscarriage occurs in the first 2-3 weeks of pregnancy, it is caused by the embryo not implanting correctly. In other cases, there is no embryo present at all and miscarriage occurs even earlier.
    Miscarriage can also be a consequence of genetic abnormalities or irregularities. In the case of surrogacy, this cause is uncommon because candidates to become gestational carriers are pre-screened, including genetic and medical tests. Malformations or scarring of the uterus are also common causes of miscarriage in women in general. Though rare in the case of surrogate pregnancies. In conclusion, miscarriage is uncommon in surrogate pregnancies. Nevertheless, intended parents should be emotionally prepared for any unexpected event that may occur. And should have addressed what to do in case of miscarriage in the surrogacy agreement.

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    1. One risk factor for ectopic pregnancy is having had your tubes tied. In this type of pregnancy, a fertilized egg begins to grow in one of the fallopian tubes instead of in the uterus. This dangerous situation can result in a ruptured tube and significant internal bleeding. Pregnancy after tubal ligation is more likely to be ectopic than pregnancies in women who haven’t had the procedure done. 
      As you can see, a tubal ligation is an effective permanent form of birth control that leaves a minimal possibility for a pregnancy afterward. Yes, there are some cases that crop up. But, for most women, the risk is very low. 
      Just to be sure, if you have had the procedure or will have it soon, you should know the signs of pregnancy after tubal ligation. That way, if you experience any symptoms, you can seek medical attention as soon as possible. Here’s what to look for (have found it on another board, I guess it might be helpful so will paste here): 
      Vaginal Discharge: Implantation can cause light spotting and cramping. You may think it’s the start of your period, but if your full period never comes, it could be the sign that tips you off. 
      Tender Breasts: The hormonal changes associated with early pregnancy may result in pain or tenderness, swollenness, or other changes in the breasts. 
      Tiredness: Hormones are to blame again! Changes in hormones may cause you to experience fatigue, even within a week after conceiving. 
      Morning Sickness: While not all women experience this symptom, it is a tell-tale sign of pregnancy. Nausea can happen at any time of the day, although the morning is often the worst. Cravings and food aversions are other related symptoms common in early pregnancy. 
      Missed Period: If you miss a period, you could be pregnant. But, you may have missed your period for another reason. The good news is after you’ve missed a period, you can take a home pregnancy test that’s likely to be accurate. 
      If you’re not sure, you can always take a home pregnancy test or see your gynecologist. That way, you’ll have peace of mind knowing whether or not you’re pregnant, and address any other medical issues that you may be experiencing. 

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  12. Want we or not, but this is a huge concern of many patients. But if we google abit, we might find sth like ''Since the first IVF baby was born in 1978, scientists have raised concerns about potential birth defects and health problems in children conceived by IVF. Most of the children appear healthy, but a small increase in health problems (Such as low birth weight, premature birth and birth defects, has been reported.)'' Fertility treatment is often associated with common risk factors. Aside from the IVF technology itself. such as being older mums or having twins or triplets, which are more likely to be delivered prematurely and have a lower birth weight. No major epigenetic differences in babies conceived by IVF have been found so far!! IVF technology has only LITTLE impact on epigenetic changes, and potentially future health.

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  13. Having made the first payment of 8 k euro, we we’ve been waiting for a match with gestational carrier for around 10 weeks. Our next payment (7 900 euro) is scheduled on the day of eggs retrieval. I’m still very overwhelmed, a bit worried about hormonal stimulation (Mainly because I’m afraid to do anything wrong). Am a bit afraid of eggs retrieval surgery in general. But still I have this very warm feeling deep in my heart that it will work for us. Hoping so much.

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  14. Found this on the internet~
    The chances of giving birth to a healthy baby after using IVF depend on various factors, including:
    Maternal age. The younger you are, the more likely you are to get pregnant and give birth to a healthy baby using your own eggs during IVF. Women age 41 and older are often counseled to consider using donor eggs during IVF to increase the chances of success.
    Embryo status. Transfer of embryos that are more developed is associated with higher pregnancy rates compared with less developed embryos (day two or three). However, not all embryos survive the development process. Talk with your doctor or other care provider about your specific situation.
    Reproductive history. Women who've previously given birth are more likely to be able to get pregnant using IVF than are women who've never given birth. Success rates are lower for women who've previously used IVF multiple times but didn't get pregnant.
    Cause of infertility. Having a normal supply of eggs increases your chances of being able to get pregnant using IVF. Women who have severe endometriosis are less likely to be able to get pregnant using IVF than are women who have unexplained infertility.
    Lifestyle factors. Women who smoke typically have fewer eggs retrieved during IVF and may miscarry more often. Smoking can lower a woman's chance of success using IVF by 50 percent. Obesity can decrease your chances of getting pregnant and having a baby. Use of alcohol, recreational drugs, excessive caffeine and certain medications also can be harmful.
    Taking all those things into consideration, the repro center is not the only one factor which is responsible for the successful outcome. One should be just realistic.

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    1. The factors of maternal health affecting recurrent implantation failure include:
      Body weight – overweight and obese patients lifestyle regime of diet and regular exercise is recommended. For the underweight patient review by dietician is needed. Smoking – needs to cease. Systemic diseases such as diabetes need to be managed adequately by the treating physician. Blood clotting disorders and autoimmune disorders antiphospholipid syndrome may affect miscarriage rates simple immune therapy such as heparin injections may be indicated. We were kindly explained all those by our dr at Biotex, Kiev. As for the treatments to improve sperm quality or overcome sperm issues include: The use of antioxidants (Such as zinc can improve sperm quality). Lifestyle changes are encouraged to improve sperm quality. Frequent ejaculation. ICSI is a well proven way of selecting and then fertilising an egg with better quality sperm.

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    2. We've recently had a transfer. Due to recent researches we were recommended to put in two, being them blasts (you know, day-5 transfers are becoming more common. And this is just the way they usually perform it in our Biotexcom clinic). But this was also our initiative to talk about our preference for a double-embryo transfer at our first appointment. Of course, the number you put it depends on the age, quality and quantity of your particular embryos. Also your specific medical history. But if there is the chance why not to take it?! So everything's going on smoothly for us. We got plenty of instructions for before and after transfer period. Except meds these are the general ones: Some bed rest - That is plan to rest in bed for a total of 3 days (including the day of transfer) immediately following your embryo transfer. The position you are in is of no consequence. So pick any position that makes you comfortable. You may get up occasionally to use the bathroom and freshen-up. Please avoid showers or baths. Try to be as relaxed as possible. Have vaginal rest - just nothing in vagina: No tampons, no sexual relations of any kind until otherwise specified. No bathing - no baths, hot tubs or swimming (pools, lakes, oceans) for two weeks. Showers are OK. No heavy lifting - Nothing over 10 lbs at a time. Avoid strenuous activities such as furniture moving, weight lifting, etc. No high impact exercise. Avoid high intensity exercise such as jogging, running, step aerobics or jumping rope. Light to moderate walking and leisurely hiking is OK and may help you to feel well. Minimaze caffeine. One or less daily caffeinated drink intake (coffee, tea, cola beverage). Avoid over the counter herbal medications. - That is literally no herbal supplements; Tylenol is OK for headaches, cramps. Avoid contact with toxic fumes and substances such as gasoline, paint, paint thinners, chlorine and ammonia. If you cannot avoid them, be sure the area is well ventilated. Get adequate rest - do not get overly fatigued. Eat and drink a well-balanced, nutritional diet. Remember to include plenty of fruits and vegetables and fluids to avoid constipation, which may be caused by progesterone. Finally do not panic!! Remember that mild cramping and/or a small amount of pink, dark red or brown vaginal spotting are normal following embryo transfer for up to two weeks, sometimes longer. Fingers crossed.. Officially in 2ww club.. Baby dust to all.

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    3. Thought this might be interestig for you~
      Symptoms of pregnancy: the classic clues
      Tender, swollen breasts . As early as two weeks after conception, hormonal changes may make your breasts tender, tingly or sore. Or your breasts may feel fuller and heavier.
      Fatigue and tiredness also ranks high among early symptoms of pregnancy. During early pregnancy, levels of the hormone progesterone soar. In high enough doses, progesterone can put you to sleep. At the same time, lower blood sugar levels, lower blood pressure and increased blood production may team up to sap your energy during your pregnancy.
      Slight bleeding or cramping
      Sometimes a small amount of spotting or vaginal bleeding is one of the first symptoms of pregnancy. Known as implantation bleeding, it happens when the fertilised egg attaches to the lining of the uterus - about 10 to 14 days after fertilisation. This type of bleeding is usually a bit earlier, spottier and lighter in colour than a normal period and doesn't last as long. Some women also experience abdominal cramping early in pregnancy. These cramps are similar to menstrual cramps.
      Nausea with or without vomiting . Morning sickness, which can strike at any time of the day or night, is one of the classic symptoms of pregnancy. For some women, the queasiness begins as early as two weeks after conception. Nausea seems to stem at least in part from rapidly rising levels of estrogen, which causes the stomach to empty more slowly. Pregnant women also have a heightened sense of smell, so various odors - such as foods cooking, perfume or cigarette smoke - may cause waves of nausea in early pregnancy. There are some hints and tips to help combat the effects of morning sickness.
      Food aversions or cravings
      When you're pregnant, you might find yourself turning up your nose at certain foods, such as coffee or fried foods. Food cravings are common too.
      Headaches.
      Constipation is another common early symptom of pregnancy. An increase in progesterone causes food to pass more slowly through the intestines, which can lead to constipation.
      Mood swings.
      Faintness and dizziness. As your blood vessels dilate and your blood pressure drops, you may feel lightheaded or dizzy. Early in pregnancy, faintness also may be triggered by low blood sugar.
      Raised basal body temperature. Your basal body temperature is your oral temperature when you first wake up in the morning. This temperature increases slightly soon after ovulation and remains at that level until your next period. If you've been charting your basal body temperature to determine when you ovulate, its continued elevation for more than two weeks may mean that you're pregnant.
      Fingers crossed. All the very best to you!

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    4. I'd recommend to see a GP as soon as you feel sth is going wrong. They will look at your medical history and give you a physical examination.
      They may also recommend some lifestyle changes to help fertility.
      Unless there are reasons that may put you at high risk of infertility, you'll usually be considered for infertility investigations and treatment.
      If appropriate, your GP can refer you to a fertility specialist at an NHS hospital or fertility clinic. He/she will ask about your fertility history. He/she may carry out a physical examination. You may have tests to check the levels of hormones in your blood. Also how well your ovaries are working. You may also have an ultrasound scan or X-ray to see if there are any blockages or structural problems. Your partner may be asked for a semen sample to test sperm quality.
      If IVF is the best treatment for you, the specialist will refer you to an assisted conception unit. Once you're accepted for treatment at the assisted conception unit, you and your partner will have blood tests for HIV, hepatitis B and hepatitis C, and to check if you're immune to rubella. Your cervical screening tests should also be up to date.
      The specialist will investigate the amount of eggs in your body and their quality (your ovarian reserve) to estimate how your ovaries will respond to IVF treatment.
      This can be assessed by measuring AMH in your blood, or by counting the number of egg-containing follicles, using a vaginal ultrasound scan.
      Your specialist will then discuss your treatment plan with you in detail and talk to you about any support or guidance you may find helpful.
      This is the possible continuation. But it all depends on the case.

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    5. Once I was recommended trying the following. 
      Minimizing exposure to toxic chemicals. 
      No drinking unfiltered tap water. 
      Aiming to eat an optimal fertility diet. Here what should we eat to boost fertility. 
      Organic meat in small quantities, game, small deep sea fish like sardines and red snapper, organic legumes home cooked (not canned). Whole grains, nuts, seeds, vegetables and fruit in season, organic where possible. Increase your consumption of good fats and avoid dangerous fats. Good fats include monounsaturated fats in olive oil, polyunsaturated fats in oily fish and nuts and midchain fatty acids found in coconut oil. For cooking use clarified butter (ghee) or coconut butter (without flavor) as they do not become unstable when heated. For non-heated oil requirements (salads etc) use cold pressed olive oil, flaxseed oil and nut oils. 
      Then avoid dangerous fats. 
      Minimize animal-derived estrogens. 
      Avoid the two most common allergens. 
      Have an STD check. 
      Allow yourself 120 days before trying to conceive. It's crucial to follow a good preconception plan for a minimum of 4 months before conception. A baby is a 50-50 product of his or her parents ~ therefore optimizing the quality of eggs and sperm is of paramount importance. 
      Avoid coffee, smoking and alcohol. 
      Take a good quality preconception and pregnancy supplement 
      Some of the key nutrients for fertility are: 
      Zinc, Selenium, Magnesium, Calcium, B12, B6, Folic acid, Vitamin C, Omega-3 fats.

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    6. I should say it's vital to choose a good clinic from thousands of others. One should look for the high live birth rates first. Then I'll be super nice if a clinic has all modern equipment. If it lets its staff to participate in overseas experts' gatherings for them to exchange the knowledge. Not the last factor is costs. Here one should remember it IS possible to find best services for reasonabl prices, just some more time for research and talking to more people on the internet. No haste decisions should be made with a clinic's choice as it's half way to success.

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  15. There are several options that can be used at the stage of fertilization to try to increase the chances of a successful pregnancy.
    ICSI is a good option when male infertility is a factor. In this procedure a single healthy sperm is injected directly into an egg.
    Assisted hatching is a procedure where a tiny hole is made in an embryo’s outer membrane to try to increase the rate of implantation after transfer.
    PGS or PGD can help to ensure that only healthy embryos are transferred. As genetic abnormality is a leading cause of miscarriage, this testing is often helpful in cases of recurrent pregnancy loss. Within 3-6 days after fertilization, embryos are evaluated for transfer: Daily monitoring helps experts decide which embryos have the best chance of surviving transfer, and IVF lab reports keep you informed of their progress.

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  16. Those are well known facts. Chances of having a healthy baby using IVF depend on many factors, such as a woman's age and the cause of infertility. In addition, IVF can be time-consuming, expensive and invasive. The chances of giving birth to a healthy baby after using IVF depend on various factors, including:
    ''Maternal age. The younger you are, the more likely you are to get pregnant and give birth to a healthy baby using your own eggs during IVF. Women age 41 and older are often counseled to consider using donor eggs during IVF to increase the chances of success.
    Embryo status. Transfer of embryos that are more developed is associated with higher pregnancy rates compared with less developed embryos (day two or three). However, not all embryos survive the development process. Talk with your doctor or other care provider about your specific situation.
    Reproductive history. Women who've previously given birth are more likely to be able to get pregnant using IVF than are women who've never given birth. Success rates are lower for women who've previously used IVF multiple times but didn't get pregnant.
    Cause of infertility. Having a normal supply of eggs increases your chances of being able to get pregnant using IVF. Women who have severe endometriosis are less likely to be able to get pregnant using IVF than are women who have unexplained infertility.
    Lifestyle factors. Women who smoke typically have fewer eggs retrieved during IVF and may miscarry more often. Smoking can lower a woman's chance of success using IVF by 50 percent. Obesity can decrease your chances of getting pregnant and having a baby. Use of alcohol, recreational drugs, excessive caffeine and certain medications also can be harmful.''

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    Replies
    1. If we're talking about surrogacy. Most fertility clinics worldwide require surrogates to meet the following general qualifications:
      Be in good physical and mental health. Have carried and delivered at least one child. Have had pregnancies that were all free of complications and were full-term. Be less than 43 years of age (some clinics will accept older woman in certain circumstances. Others have younger age cut-offs for all surrogates). Be in a stable living situation and not smoke or abuse alcohol. That's said, the environment the baby's growing in is vital.

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  17. It's well known that usually PGD testing ranges from approximately $2k to $5k and is not covered by most insurance companies. Also not all IVF centers do PGD. The experimental techniques require great expertise and should only be done by qualified personnel. It is preferable if the lab performing PGD has a PhD or MD trained medical geneticist responsible for the PGD laboratory. If you are considering doing PGD, make certain the laboratory is experienced, does a large number of cases, and is certified. Ask your doctor at the IVF clinic or the lab director the following questions: What training has the PGD laboratory personnel who are performing the testing have? How long have they been doing the procedure? When will you get the results of the PGD? What will happen if all the embryos are genetically abnormal? What the clinic’s success rate is for frozen embryo transfer following embryo biopsy?

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    1. PGD testing is not accurate. This is because only one cell is tested. All the remaining ones are left untouched so dr cannot evaluate the results 100 per cent. Thus PGD is considered to be a safe method, there are still some risks. In other words, this IS invasion to the embryo. And it can cause damage to it, you want this or no. So a lot depends on the professional performing the test. I think your suggested questions to ask will help to find the best lab.

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  18. Seems I've alredy shared this. But what I wanted to say is that the baby's health does not purely depend on the meds taken, ivf procedure etc. We should not also neglect so called ''Do'' and ''Don't'' lists for the woman who carries the baby. We all know that probably the biggest list of don’ts for pregnant women involves food. So this list says, during pregnancy, a woman should avoid: Raw meat and shellfish. For example, uncooked seafood, including oysters, mussels, and clams. Also avoid rare or undercooked beef and poultry. These can be contaminated with salmonella. Also Deli meats which can be contaminated with listeria. This is the bacteria that can cross the placenta and infect your developing baby. An infection in utero could lead to blood poisoning. Then this is fish with high levels of mercury. Fish such as shark, king mackerel, swordfish, and tilefish. Smoked seafood: Avoid lox, kippered fish, jerky, or nova style salmon. There’s a risk that this refrigerated, smoked seafood could be contaminated with listeria. Raw eggs: This includes foods that contain raw eggs, so be wary of homemade Caesar dressings, Hollandaise sauces, mayonnaise, and certain custards. Raw eggs can pose a risk of salmonella. Soft cheeses: Some imported soft cheeses can have listeria, so steer clear of soft cheeses like Roquefort, feta, Gorgonzola, Camembert, and Brie. Mexican cheeses such as queso blanco and queso fresco should also be avoided, unless they’re made from pasteurized milk. Unpasteurized dairy: These products could contain listeria. It seems extensive, right? While it’s always important to eat a balanced diet, pregnancy is an especially critical time. In your daily mail plan, try to incorporate lean proteins, healthy fats, lots of fresh, vegetables and fruits, water. Our surrogate told us she and others were being explained all these things at BioTex – that's great, isn't it?!

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  19. My insurance didn't cover PGS either. but otherwise our insurance had been great and the only thing we paid for was about $150 for meds, $2000 for the PGS, pays, and another $ 2000 or so for previous ICSI shot. PGS is a lot of $. And here one is right to say you have no idea of the outcome will be. It's a big decision. Of our 6 tested, three came back normal, 2 abnormal, and 1 was not tested for some reason. Though none of those 3 never made it up to bfp. Surrogacy was our next solution.

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  20. Hey there, @linda. I understand how this road might feel like. My journey is a long one. We had 3 stim cycles. The second was canceled days before retrieval (as it looked like we’d only be getting 1 or 2 follicles) due to poor response. We were cash pay (you could buy 3 small cars for the amount we spent), so having that cycle canceled hurt as it was about $5k down the drain. My first cycle we got 3 PGS normal embies. The first one took!! But I miscarried. The next 2 were BFNs. The third stim cycle gave us 1 100% PGS normal embies and 2 low level mosaics. Before my 4th FET, we did an ERA cycle to make sure we were transferring at the right time, which we were not. All of this took 2 years...So now we are looking for help from Biotexcom. Putting in all our hopes and expectations. We're about to start surrogacy plan too. Also we got to know about mitochondrial donation method. This gives me hope. So what if we could still try with own eggs?! I know to undergo such a procedure own eggs should not be damaged genetically. At least their last report says this. So I think they've got some special set of testings on own eggs before letting you into the program..
    How did your surrogacy journey end?

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  21. I agree with posters above. PGD helps much. PGD is used to test for chromosomal abnormalities in embryos. Including problems with the number of chromosomes or structural rearrangements. This aneupoidy testing may be recommended for any woman who have had multiple miscarriages; for women over 35 who have had a miscarriage; or for couples who have had multiple unsuccessful IVF cycles. PGD is also used to test embryos from couples with a genetic disease in their family which is absolutely great. PGD is known to be done on day3 embryos which usually have 4-8 cells. The risk of damaging the embryo at this point is very low though. Studies also have shown there is no increased risk of birth defects following PGD. It is important to remember that: PGD is not 100% accurate!! This is because only one cell is tested. The technique is quite challenging. It requires great expertise. So one has to be sure the lab is doing the best.
    For so long I’ve tried to stay positive, put on a brave face, and try to be happy for others. I’ve been there for friends’ baby showers, birthday parties, etc. Always with a smile, even when I’d been through another failed IVF cycle. Then I felt I just couldn't be positive and happy for others anymore. My friend and business partner told me she was pregnant. At 46 years old and from her own egg! I’m even younger! Like me, she’s been single for long...But she has her baby, and for me at that time, after long years ttc and 3 IVF cycles, I still didn't have! The unfairness of it was swallowing me.. We decided to seek for further options. Paying out of pocket was no more availale for us, so we searched for clinics abroad. Found Biotexcom which gave us hope. I'm with you – surrogacy like any other infertility treatment is aimed to make people happy with kids. This is the most important thing about it. No matter how our kids come to this world – everyone deserves to be a parent!
    That's useful you're explaining ALL things - good and bad, we just ahve to be aware of EVERYTHING. Thank you.

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  22. We're currently taking mitochondria donation +IVF route at Biotexcom. This time around, I am taking a prenatal, coq10, baby aspirin and L-carnitine (powdered form in juice) for my egg health. Coq10 especially is universally recommended for egg health and I take it in powdered form because it is cheaper and can be mixed with food. I like baby aspirin because it really does improve blood flow to reproductive organs. I think Maca is more for regulating cycles rather than improving egg health. But it can't hurt either way. Royal jelly I believe is good for it's high b-vitamin content if you believe that is an issues. Our Dr Elena Mozgovaya is amazing. Am just happy to have met he, though in this very case..Anyway, we trust the place more than the previous ones. Also for those who're going through the same path. I found it really interesting and wanted to share! It helps when you like to test early but get discouraged over a negative. I've been playing around with the different DPOs and brands. Here's the link - www.countdowntopregnancy.com/pregnancy-test/results-by-day-past-ovulation.php

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  23. I used to stress out too. I realized I was letting ttc process take up all my energy. So I had to let it go. If I didn’t get pregnant it’s okay… If I miss ovulation, that’s okay too. If I don’t get pregnant for another 3 months, that’s okay. 6 months, that’s okay. I am trusting God’s perfect timing.
    Other things I did are: I exercised frequently. Exercise helps with stress, and releases the endorphins to make you feel happier and energized. I also paid attention to what relaxes me, that could be watching my favorite movies or tv shows, pampering myself with something new, taking a walk, taking a drive, getting together with friends, eating a piece of chocolate. I do at least 1 of these things per day. As well as getting away from everything at least 1x per day- in the quiet and taking some deep breaths, reading, praying, meditating, listening.
    Taking care of yourself is important for stress management. That’s for sure, but one chooses the best options for her.

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  24. This all is not only about babies being healthy after IVF etc. There are also so many other points influencing!! For example, it's really hard to state the best interval between pregnancies. Though in medicine a short interval is defined as women who fall pregnant in less than 18 months. Long intervals extent to a gap of 60 months. The study found short intervals may affect the risk of pregnancy complications to the baby. (Such as pre-term birth, low birth weight, and small gestational age). There is also a impact on the mothers too.
    Here are some points to consider.
    'There is a burden on mothers to produce red blood cells so that babies can get folate and because mums become anaemic following the birth of a baby. It means they don’t get much time to recover from birth before pregnant again.'
    One in five women get the baby blues. So if they go into a pregnancy and haven’t dealt with their post natal depression then they will definitely have issues again during that pregnancy as they haven't left time to treat it adequately.'
    I believe it's better consult your doc any time you feel confused.

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  25. For as much thought and worry as parents put into figuring out when to have another child, there really is no single best time to have another child. There are benefits and drawbacks to having children spaced closely together just as there are pros and cons of having kids spaced further apart. It all depends on your particular family dynamic and what you can handle or want for your family. Here are some thoughts as for 12 to 18 month gap between kids~
    'In general, siblings that are closer in age demonstrate less sibling rivalry and the kids play together well, which many parents love. The reason for this is because the first child is still too young to have developed a strong sense of identity or jealousy. They welcome a playmate with open arms.
    Another reason parents consider under two years to be the best time to have another child is to condense all of the sacrifices and work that go into raising young children into one time period. When children are spaced close together one parent may decide to stay home with them until they are in school. This can save on childcare costs and if and when the parent does decide to re-enter the workforce he or she will have been out of it for less time, making it easier to transition into becoming a working parent.
    The drawbacks to having kids close together are the intense needs of toddlers and babies and the toll on the mother’s body. When you have two young children you have two sets of diapers, two kids who may not sleep through the night, two kids to potty train. Everything is doubled, but then it’s over and done with.
    Additionally, the physical toll on the mother’s body may be hard to bear. Her body is just recovering from the previous birth and she may still be breastfeeding. You may be forced to wean your first child before you are ready.' Hope this helps.

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  26. Sorry you've found yourself here but welcome. I really hope this message will find you healthy and full of strength. Fulfilling the family is a sacred wish for all of us though sometimes more time when expected is needed. Unfortunately we aren't the ones to rule here. The thing we can do is seeing a qualified expert who will guide you through the fertility difficulties. Also living a healthy life, eating well, having active rests and good sleeps. On the whole I'd summarize some things to consider trying:
    A sperm friendly lubricant. A supplement with Myo-Inositol. Extra vitamin B6 and Zinc. Folic Acid. Acupuncture. Drinking more water. Continue tracking your BBT & using an OPK. Getting 7-8 hours sleep. Getting to the right BMI. Eating fertility friendly foods. Stay well xx

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